WHAT IS EXPAREL?

• EXPAREL is a long-lasting, non-opioid option for postsurgical pain control.
• EXPAREL uses a proprietary multivesicular liposome (pMVL) technology, an advanced drug delivery platform designed to deliver bupivacaine over time.1 This slow release makes it possible for EXPAREL to provide long-lasting postsurgical pain control with just a single dose for up to 72 hour long.
• The pMVL technology and versatility of administration enables infiltration into the surgical site to produce local analgesia, in the fascia! plane to produce regional analgesia as a regional field block or, in adults, as an interscalene brachil plexus nerve block. EXPAREL may be used across surgical procedures, especially rectal surgery, and has demonstrated improved clinical and economic outcomes.
• EXPAREL has a proven safety and tolerability profile and is the first and only FDA-approved long-lasting local analgesic for ages 6 and above

EXPAREL works at the site of care. Your doctor places EXPAREL into the surgical site at the start or end of the procedure.

EXPAREL is long-lasting. EXPAREL is specially designed to slowly release a medicine called bupivacaine that numbs the surgical area for an extended period of time. EXPAREL can help during the first few days after surgery when pain relief is needed the most.

EXPAREL is not an opioid, it can help reduce or eliminate the need for opioids after surgery.* Opioids may cause sleepiness (sedation), constipation, and nausea and/or vomiting, which can negatively impact your recovery after surgery.

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WHAT CAN CLINICIANS AND PATIENTS EXPECT WITH EXPAREL?
When used as part of a multimodal pain management regimen, clinicians and patients can expect to see long-lasting pain control with a decrease in opioid consumption following a single dose of EXPAREL.* There are no catheters, pumps, or other devices needed to deliver EXPAREL.

HOW EXPAREL CAN HELP ENHANCE YOUR RECOVERY 

EXPAREL is a local anesthetic that numbs the area of the body where 1b,e---' surgery is performed. It can help control pain for the first 2-4 days surgery, when you need relief the most. See how EXPAREL is different from other pain relief options:

• Avoids opioid-related side effects or addiction concerns as a non-addictive, non-opioid medicine
• Provides long-lasting pain relief up to 3 days after surgery*
• Enables you to leave the hospital sooner. After some surgeries, you can even leave the same day
• Reduces the need for opioids in both adults and children, as shown in clinical trialst
• Enhances your recovery so you can return to everyday tasks earlier